REZUMAT
Nu exista suficiente date in privinta tumorilor tiroidiene la pacientii diagnosticati cu tumori neuroendocrine, despre care se stie ca avand un fond genetic complex, inca incomplet elucidat. Prezentam cazurile a 2 pacienti cu tumori neuroendocrine la care s-a diagnosticat si un nodul solitar tiroidian. Desi prima suspiciune a fost de metastaza tirodiana, punctia cu ac fin, ca si examenul histo-patologic postoperator au aratat o patologie tirodiana intrinsica. Primul caz este al unei paciente de 59 ani, care a suferit in urma cu 1 an spleno-pancreasectomie pentru carcinom neuroendocrin bine diferentiat. In timp ce markerii neuroendocrini au fost crescuti postoperator, s-a diagnosticat un nodul tiroidian de 3 cm. Punctia cu ac fin a aratat epiteliu hiperplastic folicular. Examenul histologic a descris aspect de adenom microfolicular trabecular, embriofetal. Al doilea caz este al unui pacient de 51 ani, care a suferit hemicolectomie dreapta pentru tumora neueondocrina de valva ileocecala, la varsta de 47 ani. Indexul PCNA a fost mare (50-60%). Nu s-a inregistrat sindrom hormonal de-a lungul a 4 ani de evolutie, dar s-a diagnosticat un nodul tiroidian stang de 1 cm, la care examenul histopatologic postoperator a stabilit diagnosticul de carcinom papilar.

ABSTRACT
There are no special data related to the thyroid tumors in patients diagnosed with neuroendocrine tumors, which are known to have a complex genetic background, yet incompletely elucidated. We present two patients known with entero-pancreatic tumors who were diagnosed with a solitary thyroid nodule. Also the first suspicion was a metastasis of the primary tumor, the fine needle aspiration biopsy (FNAB) and later the anatomical report after surgery pointed an intrinsic thyroidal pathology. The first case, a 59-years old female has one year history of pancreatic and spleen resection for well differentiated neuroendocrine carcinoma. While having high serum neuroendocrine markers after surgery, a left thyroid node of 3 cm is found. The FNAB suggested hyperplasic follicular epithelium. The pathological exam after surgery found a micro-follicular and trabecular embryo-fetal adenoma. The second case, a 51-years old male patient suffered a right hemicolectomy for neuroendocrine tumor of ileocecal valve at age of 47. The PCNA index was high (of 50-60 %) with no hormonal syndrome for 4 years, when a left thyroid nodule of 1 cm was discovered. The histological exam revealed a papillary carcinoma.